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Brand name: cozaar
Generic name: Losartan
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In this population, Cozaar reduces the rate of progression of nephropathy as measured by the occurrence of doubling of serum creatinine or end stage renal disease (need for dialysis or renal transplantation) (see CLINICAL PHARMACOLOGY, Pharmacodynamics and Clinical Effects). When pregnancy is detected, Cozaar should be discontinued as soon as possible. Treatment with Cozaar reduced the risk of stroke by 25% relative to atenolol (p=0. Cozaar was generally well tolerated as evidenced by a similar incidence of discontinuations due to side effects compared to placebo (19% for Cozaar, 24% for placebo). Cozaar 25 mg, Cozaar 50 mg, and Cozaar 100 mg may also contain carnauba wax. There were no significant differences in the rates of these endpoints between the Cozaar and atenolol groups. Of the patients still taking study medication, the mean doses of Cozaar and atenolol were both about 80�mg/day, and 15% were taking atenolol or losartan as monotherapy, while 77% were also receiving hydrochlorothiazide (at a mean dose of 20�mg/day in each group). Treatment with Cozaar resulted in a 16%�risk reduction in this endpoint (see Figure�4 and Table�3). 5�mg) was added first and, if needed, the dose of Cozaar or atenolol was then increased to 100�mg once daily. Patients were randomized to receive once daily Cozaar 50�mg or atenolol 50�mg. Cozaar was effective in reducing blood pressure regardless of race, although the effect was somewhat less in Black patients (usually a low-renin population).

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